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Glehnia and Rehmannia Combination (Yi Guan Jian) was first published as One Linking Decoction (Yi Guan Jian) in The Continuation of Famous Physician’s Cases Organized by Categories, written by Wei Zhi-Xiu in 1770. The phrase “One Linking” refers to the formulas ability to deal with a variety of disparate patterns, all stemming from the single diagnosis of Liver Blood and Yin deficiency with Qi stagnation.

The structure of Glehnia and Rehmannia Combination is relatively simple. Lycium fruit and Dong quai root nourish Liver Blood while raw Rehmannia root clears Empty Heat. Raw Rehmannia root also ensures adequate Kidney Yin. Glehnia root moistens the Stomach Yin, and Ophiopogon tuber moistens the Lung Yin when they have become injured by the combined effects of stasis Heat and Empty Heat. Melia fruit is the sole bitter element among all the sweet-tasting tonics. It serves to regulate stagnant Liver Qi, and also ensures the formula is not too cloying to a compromised Middle Burner.